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Molecular Discovery Seminar Series

All seminars are given at NCI-Frederick on Thursdays at 10:00am in Building 376, Conference Room 121.

Fall 2017

  • Sep 14Brian Bachmann (Vanderbilt Univ)
    "Discovery of primary tumor cell selective effector molecules using single cell multiplexed activity metabolomics"
  • Sep 21Sam Achilefu (Washington Univ in St. Louis)
    “Light-Mediated Cancer Imaging and Treatment”
  • Oct 05M.G. Finn (Georgia Tech)
  • Nov 02Sid Hecht (Arizona State Univ)
  • Nov 09Catherine Leimkuhler Grimes (Univ of Delaware)
  • Nov 16John Denu (Univ of Wisconsin, Madison)
  • Nov 30Paola Castaldi (AstraZeneca)
  • Dec 07Bing Xu (Brandeis Univ)

Spring 2017

  • Jan 12Dustin Maly (Univ of Washington)
    “Allosteric Modulation of Protein Kinases with Small Molecule Inhibitors”
  • Mar 23Michael Rossmann (Purdue Univ)
    “The Structure of Zika Virus”
  • Mar 30Alexei Demchenko (Univ of Missouri, St Louis)
    “From Stereocontrolled Glycosylation to the Automated Oligosaccharide Synthesis”
  • Apr 13Ting Xu (Univ of California, Berkeley)
    “Toward Protein/Peptide-based Functional Hybrid Materials”
  • Apr 20Dennis Dougherty (California Institute of Technology)
    “High-Precision Studies of Drug-Receptor Interactions in the Nicotinic Receptor”
  • Apr 27Steven Zimmerman (Univ of Illinois, Urbana)
    Targeting the DNA and RNA That Causes Disease Using Small Molecules and Polymers”
  • May 04 Eric Schmidt (Univ of Utah)
    “Accessing novel structural and bioactivity classes of marine natural products”
  • May 11Chris Vanderwal (Univ of California, Irvine)
    “Synthesis Strategies to Address Bioactive Natural Product Families”

Fall 2016

  • Sep 8Phil Cole (Johns Hopkins Univ)
    "Bivalent Approaches to Drug Discovery"
  • Sep 29Bruce Armitage (Carnegie Mellon Univ)
    “Fluorescence Imaging Reagents Based on RNA Aptamers, Synthetic Polymers and Fluorogenic Cyanine Dyes”
  • Oct 6Mark Distefano (Univ of Minnesota)
    “Protein Lipid Modification: New Chemistry and New Biology”
  • Oct 20Gary Martin (Merck)
    “Evolving NMR Capabilities: The Impact on What is Possible”
  • Oct 27Bradley Smith (Univ of Notre Dame)
    “Near-infrared Fluorescent Multivalent Molecular Probes for Biological Imaging”
  • Nov 3Danzhou Yang
    “Structure and Function of DNA G-quadruplexes and Its Potential as Anticancer Drug Target”
  • Nov 10John Magnani (GlycoMimetics)
    “The design, evaluation and clinical development of novel glycomimetic drugs for inflammatory disease and cancer”
  • Nov 17Dustin Maly (Univ of Washington)
    “Allosteric Modulation of Protein Kinases with Small Molecule Inhibitors”
  • Dec 8Eric Martin (Novartis)
    "Profile-QSAR Gen 2: Deep learning Kinase IC50 predictions for novel compounds as accurate as 4-pt IC50s"

Spring 2016

Fall 2015

Spring 2015

Fall 2014

Spring 2014

Fall 2013

Spring 2013

Fall 2012

Spring 2012

Fall 2011

Spring 2011

Fall 2010