1) Métifiot M, Johnson BC, Kiselev E, Marler L, Zhao XZ, Burke TR, Marchand C, Hughes SH, Pommier Y.
Selectivity for strand-transfer over 3'-processing and susceptibility to clinical resistance of HIV-1 integrase inhibitors are driven by key enzyme-DNA interactions in the active site.
Nucleic Acids Res. 44: 6896-906, 2016.
In Press.
[Journal]
2) Hogan Megan, Bahta Medhanit, Tsuji Kohei, Nguyen Trung X, Cherry Scott, Lountos George T, Tropea Joseph E, Zhao Bryan M, Zhao Xue Zhi, Waugh David S, Burke Terrence R, Ulrich Robert G.
Targeting Protein-Protein Interactions of Tyrosine Phosphatases with Microarrayed Fragment Libraries Displayed on Phosphopeptide Substrate Scaffolds.
ACS Comb Sci. 21: 158-170, 2019.
[Journal]
3) Zhao Xue Zhi, Tsuji Kohei, Hymel David, Burke Terrence R.
Development of Highly Selective 1,2,3-Triazole-containing Peptidic Polo-like Kinase 1 Polo-box Domain-binding Inhibitors.
Molecules. 24, 2019.
[Journal]
4) Lountos George, Zhao Xue Zhi, Kieselev Evgeny, Tropea Joseph, Needle Danielle, Pommier Yves, Burke Terrence, Waugh David.
Identification of ligand binding hot spot and structural motifs replicating aspects of tyrosyl-DNA phosphodiesterase I (TDP1) phosphoryl recognition by crystallographic fragment cocktail screening.
Nuclei Acids Res. 1: 1, 2019.
[Journal]
5) Smith Steven J, Zhao Xue Zhi, Burke Terrence R, Hughes Stephen H.
HIV-1 Integrase Inhibitors That Are Broadly Effective against Drug-Resistant Mutants.
Antimicrob. Agents Chemother. 62, 2018.
[Journal]
1) Burke TR, Gao YR, Voight JR, Wei CR (submitted in 2000) Sh2 Domain Binding Inhibitors.
Patents pending: 01964256.0 (EP application); PCT/US01/26078 (PC application); 60/226,671 (US application); 10/362,231 (US application); 2001285133 (AU application); 2419870 (CA application).
2) Bottaro DP, Atabey NP, Breckenridge DP, Burke TP, Gao YP, Yao ZP (submitted in 1999) Inhibition Of Cell Motility And Angiogenesis By Inhibitors Of The Grb2 Sh2-domain.
Patents pending: 00992431.7 (ES application); 00992431.7 (FR application); 00992431.7 (GB application); 00992431.7 (IT application); 531405/2001 (JP application); 00992431.7 (CH application); 00992431.7 (DE application).
3) Burke TR, Gao YR, Yang DR, Yao ZR (submitted in 1999) Phenylalanine Derivatives.
Patent pending: 2855415 (CA application).
4) Pommier Y, Burke T, Neamati N, Zhaiwai L (submitted in 1999) Hydrazide Inhibitors Of Hiv-1 Integrase.
Patents pending: PCT/US00/06361 (PC application); 60/124,302 (US application).
5) Burke TR, King CR, Yao ZR (submitted in 1999) Acylated Oligopeptide Derivatives Having Cell Signal Inhibiting Activity.
Patent pending: 09/236,160 (US application).